In the 1970s, microbiologist Satoshi Ōmura at Japan's Kitasato Institute isolated a soil bacterium that produced compounds effective against parasitic worms. Working under a partnership with Merck, parasitologist William C. Campbell's team refined these compounds into ivermectin, a veterinary treatment approved in 1981 and later adapted into Mectizan, approved for human use in 1987 to treat river blindness. Merck committed to donating Mectizan indefinitely to combat the disease, and Ōmura and Campbell shared the 2015 Nobel Prize in Physiology or Medicine for the discovery.
1887
The oldest surviving rotary snowplow in the world
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Steam and the inexpensive electricity it could produce brought about dramatic technical growth in the United States. Developed during the last century, reliable and efficient steam engines were the forerunners of today's massive generating facilities. A rare survivor of the period, the Pratt facility is the oldest generating plant of its kind in the Northeast and embodies the typical features of engines in a row, open-front marble switchboard, and an observation balcony at street level.
The city of Shreveport could not justify the cost of building a water distribution system solely for the purpose of supplying potable water. It was a series of disastrous fires in the 1880s that galvanized support for a pumping facility that would provide ample water for firefighting.
Innovations
The city of Shreveport could not justify the cost of building a water distribution system solely for the purpose of supplying potable water. It was a series of disastrous fires in the 1880s that galvanized support for a pumping facility that would provide ample water for firefighting.
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Read MoreSteam and the inexpensive electricity it could produce brought about dramatic technical growth in the United States. Developed during the last century, reliable and efficient steam engines were the forerunners of today's massive generating facilities. A rare survivor of the period, the Pratt…
Read MoreIn the 1970s, microbiologist Satoshi Ōmura at Japan's Kitasato Institute isolated a soil bacterium that produced compounds effective against parasitic worms. Working under a partnership with Merck, parasitologist William C. Campbell's team refined these compounds into ivermectin, a veterinary…
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